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Cialis

Cialis (tadalafil) is a phosphodiesterase type 5 inhibitor, which relaxes blood vessels and increases blood flow to particular areas of the body, which improves erectile function. Cialis is manufactured by Eli Lilly and contains the active ingredient tadalafil, which is an erectile dysfunction medication. Cialis is used to treat conditions such as:

  • Erectile Dysfunction (ED)- The most common sexual dysfunction in men, affecting up to 1 in 10 men around the world.
  • Pulmonary arterial hypertension (PAH)- Pulmonary hypertension, a condition in which a high blood pressure in the lungs is high, resulting in symptoms such as chest pain or shortness of breath.

Cialis is not approved by the US Food and Drug Administration (FDA) for the treatment of erectile dysfunction (ED) or pulmonary arterial hypertension (PAH). In the United States, Cialis is marketed as Eli Lilly and Company’s erectile dysfunction drug, which has been approved for sale under the brand name Cialis.

Cialis is not approved by the FDA for the treatment of PAH. In the United States, Cialis is marketed as Eli Lilly and Company’s Pulmonary Arterial Hypertension (PAH). The active ingredient in Pulmonary Arterial Hypertension is tadalafil, which is a phosphodiesterase type 5 inhibitor.

The most common sexual dysfunction in men around the world is erectile dysfunction. ED is the inability to attain or maintain an erection sufficient for sexual activity. ED is defined as the inability to achieve or maintain an erection firm enough for sexual intercourse.

Cialis Dosage

Cialis should be taken at least one hour before sexual activity. Cialis should be taken only when needed.

For most men, Cialis is not recommended for use with nitrates, because nitrates can cause a sudden drop in blood pressure, which can cause dizziness and fainting.

Do not take Cialis if you have ever had an erection that lasted more than 4 hours. Cialis should not be taken more than once every 24 hours.

Cialis should not be taken more than once a day.

Cialis Side Effects

The most common side effects of Cialis are headache, back pain, muscle aches, indigestion, and flushing. If you experience these symptoms while taking Cialis, stop taking Cialis and contact your doctor right away.

Contact your doctor if you experience severe side effects such as sudden vision loss, prolonged erection (priapism), or a painful erection lasting more than four hours. Seek immediate medical attention if you experience these symptoms.

If you experience any of these symptoms while taking Cialis, stop taking Cialis and contact your doctor right away.

Stop taking Cialis and contact your doctor if you experience a painful erection lasting more than four hours. Seek immediate medical attention if you experience a painful erection lasting more than four hours.

If you have any of the following side effects, you should seek immediate medical attention:

  • chest pain
  • indigestion
  • heartburn
  • flu-like symptoms
  • headache
  • flushing
  • feeling light-headed or short of breath

Contact your doctor or seek emergency medical treatment if you experience chest pain, shortness of breath, or fainting. This is not a complete list of possible side effects.

Cialis has been shown to cause some mild side effects. Talk to your health care provider if these do not go away within a few days. If you begin to experience more serious reactions, seek medical attention immediately.

Common side effects reported from Cialis use include:

  • Headache
  • Indigestion
  • Heartburn
  • Upset stomach
  • Gas
  • Nausea
  • Flushing

More severe side effects include:

  • Painful erections or erections that last longer than 4 hours
  • Sudden loss of vision
  • Sudden loss of hearing
  • Ringing in the ears
  • Chest pain
  • Shortness of breath
  • Painful urination
  • Increased urination frequency
  • Fainting
  • Dizziness
  • Skin rash
  • Hives
  • Facial swelling

If you experience any of these side effects, seek medical attention immediately. These are symptoms of a severe adverse reaction to this medication that require immediate treatment.

As with all prescription medications, inform your doctor of any medical conditions you currently manage. Tell them about any and all medications, prescription drugs, and supplements you are taking before starting treatment with Cialis. Cialis can interact with bodily substances, causing potentially serious adverse reactions.

Specifically, you should inform your health care provider of any alpha-blocker, antifungal, HIV protease inhibitor, or high blood pressure medication you are taking. Remember to mention any herbal products you use, especially St. John’s wort.

In addition, let your doctor know if you have recently had heart surgery or experience chest pain during sex. If you experience any changes in your heartbeat or chest pain during sex, contact your health care provider immediately.

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The information found in this article is intended to supplement, not substitute for, the expertise and judgment of our doctors, pharmacists, and nurses. If you have any concerns or questions about your health, please consult your doctor or nurse at home.

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Always take your medication exactly as your doctor or health care provider told you. Never change your dose without consulting your doctor.

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NOTE: This medicine is only for you. Do not share this medicine with others.

This is not a complete list of all side effects. If you have any concerns, please consult your doctor or nurse. Our doctors may also prescribe you other medications, including prescription drugs, over-the-counter medicines, and dietary supplements, as long as they are not affected by this medicine.

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This information is not intended to replace advice or treatment. Always consult your doctor or other health care provider with any questions you may have regarding a medical condition. A link to a source can provide a more complete list of possible sources.

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Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.

If you are taking any other type of nitrate or alpha-blocker, including D‑amino nitrate, consult your doctor before starting.

C.

Cialis (tadalafil) can interact with certain foods and beverages, including grapefruit, grapefruit juice, and alcohol, increasing your risk of side effects. Avoiding these while taking Cialis can reduce the risk of side effects.

D‑amino nitrate medications, including nitrates and nitrites, can cause a drop in blood pressure to the level which would be predicted by your blood pressure when taking them. This can amplify side effects, leading to a feeling of dizziness or fainting. If you experience chest pain, lightheaded, or fainting, seek immediate medical attention.

How to use Cialis:

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Cialis, sold in various forms such as tablets, oral pills, and topical treatments, is available in various dosages and prescribed parenthe entirety of its effectiveness.